Genital Warts Treatment, warts that appear in the genitals, are a result of the human papillomavirus (HPV) and can occur in a cluster or singular wart. Those affected with this sexually transmitted disease contracted HPV from someone who was already infected with the virus. Whether or not you can see the warts, if you have HPV, you can spread the infection. It’s important to seek treatment, as the warts are often stubborn and can cause further complications, such as cervical cancer, anal cancer, cancer of the penis, throat, or mouth cancer.